Study Reveals Slightly Higher Risk of Autism Diagnosis in Areas with More Lithium in Drinking Water
A new study published in the journal JAMA Pediatrics has found a moderate association between higher levels of lithium in drinking water and an increased risk of autism spectrum disorder (ASD) in children. The researchers, led by Dr. Beate Ritz, analyzed data from over 8,800 cases of ASD and compared it to nearly 44,000 participants who did not have the condition.
The study found that as lithium levels in water increased, so did the risk of an ASD diagnosis. Specifically, those with exposure levels at the second and third highest range had a 24-26% higher risk of ASD diagnosed in children, while those with the highest exposure level had a 46% higher risk compared to those with lower levels.
However, experts caution that this association does not imply a direct link between lithium exposure and autism diagnosis. "Any drinking water contaminants that may affect the developing human brain deserve intense scrutiny," said Dr. Ritz, adding that further research is needed to confirm the findings and explore potential mechanisms.
Lithium is an alkali metal commonly found in food, ground water, batteries, grease, and air conditioners. Its levels in US drinking water are not regulated by the US Geological Survey. The researchers chose Denmark as a study location due to its low consumption of bottled water.
The implications of this finding are complex from a public health policy perspective. On one hand, high lithium levels have been linked to reduced rates of hospitalization for psychiatric disorders and suicide. On the other hand, there is no clear mechanism by which small amounts of lithium in drinking water could lead to ASD.
Other studies have suggested connections between ASD and environmental exposures to pesticides, air pollution, and phthalates, but none of them point to a direct cause. Dr. Max Wiznitzer, director of the Rainbow Autism Center, noted that research on the effects of lithium on pregnant people taking it for mental health disorders does not show a connection with autism spectrum disorder.
The study highlights the importance of further investigation into potential environmental causes of ASD. As Dr. Ritz stated, "we have to figure out how to safely navigate" these potential risks in our everyday lives.
A new study published in the journal JAMA Pediatrics has found a moderate association between higher levels of lithium in drinking water and an increased risk of autism spectrum disorder (ASD) in children. The researchers, led by Dr. Beate Ritz, analyzed data from over 8,800 cases of ASD and compared it to nearly 44,000 participants who did not have the condition.
The study found that as lithium levels in water increased, so did the risk of an ASD diagnosis. Specifically, those with exposure levels at the second and third highest range had a 24-26% higher risk of ASD diagnosed in children, while those with the highest exposure level had a 46% higher risk compared to those with lower levels.
However, experts caution that this association does not imply a direct link between lithium exposure and autism diagnosis. "Any drinking water contaminants that may affect the developing human brain deserve intense scrutiny," said Dr. Ritz, adding that further research is needed to confirm the findings and explore potential mechanisms.
Lithium is an alkali metal commonly found in food, ground water, batteries, grease, and air conditioners. Its levels in US drinking water are not regulated by the US Geological Survey. The researchers chose Denmark as a study location due to its low consumption of bottled water.
The implications of this finding are complex from a public health policy perspective. On one hand, high lithium levels have been linked to reduced rates of hospitalization for psychiatric disorders and suicide. On the other hand, there is no clear mechanism by which small amounts of lithium in drinking water could lead to ASD.
Other studies have suggested connections between ASD and environmental exposures to pesticides, air pollution, and phthalates, but none of them point to a direct cause. Dr. Max Wiznitzer, director of the Rainbow Autism Center, noted that research on the effects of lithium on pregnant people taking it for mental health disorders does not show a connection with autism spectrum disorder.
The study highlights the importance of further investigation into potential environmental causes of ASD. As Dr. Ritz stated, "we have to figure out how to safely navigate" these potential risks in our everyday lives.