UK Science Minister Unveils Plan to Speed Up Animal Testing Phase-out via AI and 3D Bioprinting
A new plan aimed at reducing animal testing in scientific research has been unveiled by the UK's science minister, Patrick Vallance. The strategy focuses on increasing the use of artificial intelligence (AI) to analyze vast amounts of data about molecules and predict their safety for human exposure, as well as leveraging 3D bioprinted tissues that mimic human organs using real human cells.
The government has committed to developing new methods such as organ-on-a-chip systems, which can replicate how human organs function. This technology is expected to replace animal tests in the assessment of skin and eye irritation by the end of 2026. The plan also aims to phase out regulatory testing on animals for assessing skin sensitization by 2027.
Additionally, researchers will no longer be required to test the strength of botulinum toxin on mice by 2027, while pharmacokinetic studies β which track how a drug moves through the body over time β on dogs and non-human primates are expected to be reduced by 2030.
Lord Vallance described the plan as an "ambition" to end animal testing wherever possible and roll out alternatives as soon as they become safe and effective. The strategy has been welcomed by animal welfare groups, with one organization stating that it sets a clear ambition towards eliminating animal use in scientific research and will create a foundation for accelerating the replacement of animals.
The government's plan acknowledges that phasing out animal testing is only possible when reliable alternatives can be developed with equivalent safety for human exposure. New funding for researchers and streamlined regulations are expected to support the development of these alternative methods.
A new plan aimed at reducing animal testing in scientific research has been unveiled by the UK's science minister, Patrick Vallance. The strategy focuses on increasing the use of artificial intelligence (AI) to analyze vast amounts of data about molecules and predict their safety for human exposure, as well as leveraging 3D bioprinted tissues that mimic human organs using real human cells.
The government has committed to developing new methods such as organ-on-a-chip systems, which can replicate how human organs function. This technology is expected to replace animal tests in the assessment of skin and eye irritation by the end of 2026. The plan also aims to phase out regulatory testing on animals for assessing skin sensitization by 2027.
Additionally, researchers will no longer be required to test the strength of botulinum toxin on mice by 2027, while pharmacokinetic studies β which track how a drug moves through the body over time β on dogs and non-human primates are expected to be reduced by 2030.
Lord Vallance described the plan as an "ambition" to end animal testing wherever possible and roll out alternatives as soon as they become safe and effective. The strategy has been welcomed by animal welfare groups, with one organization stating that it sets a clear ambition towards eliminating animal use in scientific research and will create a foundation for accelerating the replacement of animals.
The government's plan acknowledges that phasing out animal testing is only possible when reliable alternatives can be developed with equivalent safety for human exposure. New funding for researchers and streamlined regulations are expected to support the development of these alternative methods.