A Breakthrough Vaccine for Anti-Aging Could Be Sitting on Pharmacy Shelves, But Few Are Taking It.
Despite being available since 2006, the shingles vaccine has not gained widespread acceptance among Americans, particularly seniors who are most at risk from the disease. The vaccine's inventor believes that its benefits extend far beyond preventing painful skin rashes to also slowing down biological aging and dementia.
Recent studies have shown that receiving the shingles vaccine is associated with a 20 percent lower chance of being diagnosed with dementia. Additionally, individuals who already had dementia and received the vaccine experienced slower disease progression and fewer deaths, suggesting potential therapeutic benefits. The vaccine's impact on cognitive decline has also been observed in other countries, including Australia and Canada.
Researchers are now eager to investigate these findings further, but financial support for further research has dwindled. According to Pascal Geldsetzer, a Stanford University researcher, securing funding has been "surprisingly hard." He believes that a randomized clinical trial would provide the most compelling evidence of the vaccine's efficacy in preventing dementia and slowing aging.
The challenges are multifaceted, including a decline in pharmaceutical investment, an NIH grant that supported initial research now being reevaluated under new leadership, and growing concerns about vaccination hesitancy even among seniors. These factors have led to low vaccination rates for shingles shots, particularly among men, people from historically marginalized groups, and those with lower incomes.
In a more ideal scenario, the vaccine might be recommended for younger individuals as well due to its potential long-term benefits in preventing chronic diseases associated with aging. At present, it is crucial for family members and healthcare providers to encourage seniors to take the shingles shot, which could have far-reaching consequences for their health and that of those around them.
With an estimated 30 percent of eligible Americans having received the shingles vaccine as of 2022, there remains a significant opportunity to maximize its value through increased research efforts and public outreach.
Despite being available since 2006, the shingles vaccine has not gained widespread acceptance among Americans, particularly seniors who are most at risk from the disease. The vaccine's inventor believes that its benefits extend far beyond preventing painful skin rashes to also slowing down biological aging and dementia.
Recent studies have shown that receiving the shingles vaccine is associated with a 20 percent lower chance of being diagnosed with dementia. Additionally, individuals who already had dementia and received the vaccine experienced slower disease progression and fewer deaths, suggesting potential therapeutic benefits. The vaccine's impact on cognitive decline has also been observed in other countries, including Australia and Canada.
Researchers are now eager to investigate these findings further, but financial support for further research has dwindled. According to Pascal Geldsetzer, a Stanford University researcher, securing funding has been "surprisingly hard." He believes that a randomized clinical trial would provide the most compelling evidence of the vaccine's efficacy in preventing dementia and slowing aging.
The challenges are multifaceted, including a decline in pharmaceutical investment, an NIH grant that supported initial research now being reevaluated under new leadership, and growing concerns about vaccination hesitancy even among seniors. These factors have led to low vaccination rates for shingles shots, particularly among men, people from historically marginalized groups, and those with lower incomes.
In a more ideal scenario, the vaccine might be recommended for younger individuals as well due to its potential long-term benefits in preventing chronic diseases associated with aging. At present, it is crucial for family members and healthcare providers to encourage seniors to take the shingles shot, which could have far-reaching consequences for their health and that of those around them.
With an estimated 30 percent of eligible Americans having received the shingles vaccine as of 2022, there remains a significant opportunity to maximize its value through increased research efforts and public outreach.