A bizarre side effect of the keto diet has been linked to a strange, itchy rash.
Researchers in Japan first identified the condition, known as prurigo pigmentosa, in 1971, mostly affecting women. The rash was characterized by red, raised, and itchy bumps on the neck, chest, and back, accompanied by patches of hyperpigmentation.
While initially seen only among keto dieters, the rash has since been linked to metabolic disorders, diabetes, bariatric surgery, and fasting as well.
Doctors are still unsure what triggers the condition but one hypothesis suggests that high levels of ketones in the blood lead to inflammation around blood vessels driven by neutrophils, which ultimately causes the rash.
Effective treatment for prurigo pigmentosa is to exit the keto diet and take an antibiotic like doxycycline.
Researchers in Japan first identified the condition, known as prurigo pigmentosa, in 1971, mostly affecting women. The rash was characterized by red, raised, and itchy bumps on the neck, chest, and back, accompanied by patches of hyperpigmentation.
While initially seen only among keto dieters, the rash has since been linked to metabolic disorders, diabetes, bariatric surgery, and fasting as well.
Doctors are still unsure what triggers the condition but one hypothesis suggests that high levels of ketones in the blood lead to inflammation around blood vessels driven by neutrophils, which ultimately causes the rash.
Effective treatment for prurigo pigmentosa is to exit the keto diet and take an antibiotic like doxycycline.