Cancer Treatment Gets Boost from Bizarre but Promising Solution: Fecal Microbiota Transplantation Pills
In a breakthrough that may change the face of cancer treatment, scientists have discovered that fecal microbiota transplantation (FMT) pills can significantly enhance the effectiveness of immunotherapy, a widely used approach to treating late-stage cancers. This game-changing development comes after two small trials published in Nature Medicine, which found that FMT pills reduced side effects and improved outcomes for patients with kidney cancer and lung/melanoma cancer.
FMT involves transplanting healthy bacteria from one person's gut into another person's gut to rebuild their microbiome, which is essential for overall health. Traditionally, FMT has been administered through colonoscopies or enemas, but a team of researchers at the Lawson Research Institute in Ontario, Canada, has successfully developed customized pill-form FMT that can be taken orally.
In the first trial, patients with advanced kidney cancer who had received immunotherapy drugs before taking FMT experienced fewer side effects and showed a higher treatment response rate compared to those who didn't receive the transplantation. In the second trial, patients with lung or melanoma cancer given both FMT and immunotherapy responded at an impressive 75-80%, significantly higher than the typical response rate for these treatments.
While the findings are promising, it's essential to note that these studies were small in size and more extensive trials are needed to confirm their results. However, this breakthrough has sparked excitement among researchers and could potentially revolutionize cancer treatment. With FMT pills, donated poop may become a game-changer for patients who wouldn't otherwise respond to standard care.
As Dr. Michael Silverman, an author of the studies, said, "This is tremendous... it had never been done in treating kidney cancer before this." The future of cancer treatment has just taken a remarkable turn with FMT pills.
In a breakthrough that may change the face of cancer treatment, scientists have discovered that fecal microbiota transplantation (FMT) pills can significantly enhance the effectiveness of immunotherapy, a widely used approach to treating late-stage cancers. This game-changing development comes after two small trials published in Nature Medicine, which found that FMT pills reduced side effects and improved outcomes for patients with kidney cancer and lung/melanoma cancer.
FMT involves transplanting healthy bacteria from one person's gut into another person's gut to rebuild their microbiome, which is essential for overall health. Traditionally, FMT has been administered through colonoscopies or enemas, but a team of researchers at the Lawson Research Institute in Ontario, Canada, has successfully developed customized pill-form FMT that can be taken orally.
In the first trial, patients with advanced kidney cancer who had received immunotherapy drugs before taking FMT experienced fewer side effects and showed a higher treatment response rate compared to those who didn't receive the transplantation. In the second trial, patients with lung or melanoma cancer given both FMT and immunotherapy responded at an impressive 75-80%, significantly higher than the typical response rate for these treatments.
While the findings are promising, it's essential to note that these studies were small in size and more extensive trials are needed to confirm their results. However, this breakthrough has sparked excitement among researchers and could potentially revolutionize cancer treatment. With FMT pills, donated poop may become a game-changer for patients who wouldn't otherwise respond to standard care.
As Dr. Michael Silverman, an author of the studies, said, "This is tremendous... it had never been done in treating kidney cancer before this." The future of cancer treatment has just taken a remarkable turn with FMT pills.