Australian conservation biologist Anthony Waddle has dedicated his career to saving frogs from the deadly chytrid fungus that is threatening hundreds of species. Eight years ago, Waddle's fascination with tadpoles sparked a lifelong passion for amphibian conservation, which he says took him on an unexpected journey.
Waddle grew up in Las Vegas, where his family struggled financially. The young boy found solace in animal trivia and spent hours clutching a binder full of facts about the creatures that fascinate him. After receiving his PhD from the University of Melbourne in 2022, Waddle set out to tackle the crisis facing frogs worldwide.
The fungus infects amphibians by exploiting their skin, which is rich in beneficial compounds that could lead to new painkillers and treatments for diseases. The disease is almost always deadly, wiping out entire populations.
To combat this threat, Waddle has developed an innovative solution: mini saunas for frogs. Working from his lab in Australia during the pandemic, he created a miniature brick structure with temperature-regulated greenhouses above it to raise frog body temperatures and stave off the fungus.
In a groundbreaking experiment, Waddle's saunas proved effective, reducing the risk of infection among frogs that spent winters in the shelters. However, not all species can be vaccinated or treated by this method. For those that cannot, Waddle is exploring gene replacement therapy to help them reintegrate into the wild.
The use of synthetic biology in conservation raises debate about ethics and unintended consequences. Some scientists, like Waddle, see it as a game-changer for saving vulnerable species. "We can't be willy-nilly slapping genes into frogs," he says. "But at the research level, we should investigate this method."
Waddle's work is being hailed by experts, who see his approach as a ray of hope in amphibian conservation. With over 40% of all frog species threatened with extinction worldwide, innovative strategies like Waddle's are desperately needed to turn the tide.
Despite the challenges he faces, Waddle remains optimistic and excited about the potential breakthroughs on the horizon. When asked what keeps him awake at night, he smiles – it's usually anticipation of new discoveries or ideas for his next experiment.
Waddle grew up in Las Vegas, where his family struggled financially. The young boy found solace in animal trivia and spent hours clutching a binder full of facts about the creatures that fascinate him. After receiving his PhD from the University of Melbourne in 2022, Waddle set out to tackle the crisis facing frogs worldwide.
The fungus infects amphibians by exploiting their skin, which is rich in beneficial compounds that could lead to new painkillers and treatments for diseases. The disease is almost always deadly, wiping out entire populations.
To combat this threat, Waddle has developed an innovative solution: mini saunas for frogs. Working from his lab in Australia during the pandemic, he created a miniature brick structure with temperature-regulated greenhouses above it to raise frog body temperatures and stave off the fungus.
In a groundbreaking experiment, Waddle's saunas proved effective, reducing the risk of infection among frogs that spent winters in the shelters. However, not all species can be vaccinated or treated by this method. For those that cannot, Waddle is exploring gene replacement therapy to help them reintegrate into the wild.
The use of synthetic biology in conservation raises debate about ethics and unintended consequences. Some scientists, like Waddle, see it as a game-changer for saving vulnerable species. "We can't be willy-nilly slapping genes into frogs," he says. "But at the research level, we should investigate this method."
Waddle's work is being hailed by experts, who see his approach as a ray of hope in amphibian conservation. With over 40% of all frog species threatened with extinction worldwide, innovative strategies like Waddle's are desperately needed to turn the tide.
Despite the challenges he faces, Waddle remains optimistic and excited about the potential breakthroughs on the horizon. When asked what keeps him awake at night, he smiles – it's usually anticipation of new discoveries or ideas for his next experiment.