Mounjaro Users Face Reversal of Health Benefits When Stopping Treatment, Study Finds
A recent study has shed light on a concerning trend among individuals who stop using Mounjaro, a weight-loss medication that combines two active ingredients to help people lose an average of 20% of their body weight. The research reveals that not only do users tend to regain weight, but they also experience a reversal in other health benefits, including reduced blood pressure and lower levels of "bad" cholesterol.
The study, known as Surmount-4, analyzed data from participants who had lost at least 10% of their body weight after receiving Mounjaro for 36 weeks. Half of the participants continued using the medication for an additional 52 weeks, while the other half switched to a placebo. The results showed that one year after stopping treatment, 82% of those who had previously achieved significant weight loss had regained at least 25% of their initial weight reduction.
The findings also indicate that greater weight regain is associated with greater reversals in measures such as waist circumference, blood pressure, and blood glucose levels. In fact, by the end of the study, participants who had regained up to 50% of their initial weight showed improvements in these areas compared to baseline values.
Experts warn that sustaining weight loss through lifestyle intervention and obesity management medications is crucial to maintaining cardiometabolic benefits and improved health-related quality of life. However, they also caution that relying solely on medication may not lead to lasting changes in eating habits or exercise behaviors, which can result in poorer diets and a higher risk of weight regain.
The study's results have implications for the long-term use of Mounjaro and other weight-loss medications. While these treatments can be effective for short-term weight loss, they may not provide sustained benefits without ongoing lifestyle support. Researchers are now exploring new strategies to support long-term weight management, including more affordable interventions that can help individuals maintain healthy habits over time.
A recent study has shed light on a concerning trend among individuals who stop using Mounjaro, a weight-loss medication that combines two active ingredients to help people lose an average of 20% of their body weight. The research reveals that not only do users tend to regain weight, but they also experience a reversal in other health benefits, including reduced blood pressure and lower levels of "bad" cholesterol.
The study, known as Surmount-4, analyzed data from participants who had lost at least 10% of their body weight after receiving Mounjaro for 36 weeks. Half of the participants continued using the medication for an additional 52 weeks, while the other half switched to a placebo. The results showed that one year after stopping treatment, 82% of those who had previously achieved significant weight loss had regained at least 25% of their initial weight reduction.
The findings also indicate that greater weight regain is associated with greater reversals in measures such as waist circumference, blood pressure, and blood glucose levels. In fact, by the end of the study, participants who had regained up to 50% of their initial weight showed improvements in these areas compared to baseline values.
Experts warn that sustaining weight loss through lifestyle intervention and obesity management medications is crucial to maintaining cardiometabolic benefits and improved health-related quality of life. However, they also caution that relying solely on medication may not lead to lasting changes in eating habits or exercise behaviors, which can result in poorer diets and a higher risk of weight regain.
The study's results have implications for the long-term use of Mounjaro and other weight-loss medications. While these treatments can be effective for short-term weight loss, they may not provide sustained benefits without ongoing lifestyle support. Researchers are now exploring new strategies to support long-term weight management, including more affordable interventions that can help individuals maintain healthy habits over time.
I'm kinda worried about Mounjaro users, you know? Stopping treatment and then regaining all that weight they lost... it's like their bodies just go back to normal or something 
. And the fact that they even lose some health benefits too is crazy talk 
! What's the point of taking a pill if you're not gonna keep at it with healthy habits, right? 
I feel like these new research findings are giving me anxiety just thinking about all those people who might be struggling to maintain weight loss and their overall health 
. We need more affordable, sustainable solutions that can help people stick to those lifestyle changes for the long haul 
!
we need to understand that weight loss isn't just about stopping treatment, it's about making sustainable lifestyle changes too 
these researchers are on the right track by looking into affordable interventions and ways to keep people motivated 
gotta make us stick to the diet & exercise plan ourselves 
I'm like totally concerned about this study on Mounjaro users who stop treatment 
. The fact that 82% of participants regained at least 25% of their initial weight reduction in just one year is pretty alarming 
.
. We need more affordable, sustainable solutions that can support people long-term 
. It's not just about the medication; it's about creating healthy habits that stick 
.
. we all know that's easier said than done, but we gotta try, right? 
This is so interesting! I had no idea that stopping Mounjaro could lead to a reversal of health benefits 
. And get this - those who regained more weight experienced even bigger reversals in their health benefits 
. Waist circumference, blood pressure, and blood glucose levels all took a hit. It's like, what happens when we stop taking care of ourselves? 
. It's time to rethink our approach to weight management...
I mean, we all know that losing weight is hard, but stopping treatment completely and expecting our bodies to magically go back to normal is just too much to ask. 
. And let's be real, we all know that exercise and healthy eating habits are the keys to sustainable weight loss, but it's way easier said than done 
. Experts are right to emphasize the importance of sustaining weight loss through a combination of medication, healthy eating habits, and regular exercise routines 
. We must prioritize evidence-based approaches that acknowledge the intricate interplay between genetics, environment, and behavior 
.
. But let's not forget that these meds are meant to be used under the guidance of a healthcare professional 
. It's not like you just start popping pills and expect to keep the weight off forever 
. The key here is finding that balance between medication and lifestyle changes 
.
But now, this Mounjaro thing is kinda scary too. All these new meds coming out and they're making us reliant on them just to lose weight 
It's like, don't get me wrong, I'm all for lifestyle changes and being healthy, but medication can be a game-changer too... it's not just about willpower. And what really gets me is that people are gonna have to deal with these reversals in their health benefits... that's just harsh 
. The fact that they're exploring new strategies now is great, but I wish we'd seen more of this research going on sooner