US President Donald Trump's claims that paracetamol causes autism have been debunked by a comprehensive review of 43 studies on the subject. The study, published in the Lancet Obstetrics, Gynaecology and Women's Health, found no evidence to suggest that maternal paracetamol use during pregnancy increases the risk of autism spectrum disorder, ADHD, or intellectual disability among children.
The gold-standard review, which has been hailed as the most rigorous analysis of the evidence to date, examined the health outcomes of over 1 million children born to mothers who used paracetamol during pregnancy. The study's authors concluded that paracetamol remains a safe option for pregnant women when taken as guided, and that the medication does not pose an increased risk of autism or other developmental disorders.
The findings directly contradict Trump's claims, which sparked anxiety among pregnant women around the world. Trump had suggested that all pregnant women should talk to their doctors about limiting the use of paracetamol while pregnant, citing a supposed link between the medication and autism. However, the new study has identified no association between exposure to paracetamol in utero and an increased risk of autism or other developmental disorders.
The researchers attribute the observed associations between paracetamol use during pregnancy and an increased risk of autism or developmental disorders to "familial and genetic factors" rather than any direct effect of the medication. They also suggest that an underlying health condition prompting regular use of paracetamol may play a more significant role in shaping neurodevelopmental outcomes.
Health experts have welcomed the study's findings, stating that expectant mothers do not need the stress of questioning whether medicine most commonly used for headaches could have far-reaching effects on their child's health. The UK's Health Secretary, Wes Streeting, has also advised women to ignore Trump's claims and reassure them that paracetamol is safe to use when pregnant and in pain or suffering a fever.
The gold-standard review, which has been hailed as the most rigorous analysis of the evidence to date, examined the health outcomes of over 1 million children born to mothers who used paracetamol during pregnancy. The study's authors concluded that paracetamol remains a safe option for pregnant women when taken as guided, and that the medication does not pose an increased risk of autism or other developmental disorders.
The findings directly contradict Trump's claims, which sparked anxiety among pregnant women around the world. Trump had suggested that all pregnant women should talk to their doctors about limiting the use of paracetamol while pregnant, citing a supposed link between the medication and autism. However, the new study has identified no association between exposure to paracetamol in utero and an increased risk of autism or other developmental disorders.
The researchers attribute the observed associations between paracetamol use during pregnancy and an increased risk of autism or developmental disorders to "familial and genetic factors" rather than any direct effect of the medication. They also suggest that an underlying health condition prompting regular use of paracetamol may play a more significant role in shaping neurodevelopmental outcomes.
Health experts have welcomed the study's findings, stating that expectant mothers do not need the stress of questioning whether medicine most commonly used for headaches could have far-reaching effects on their child's health. The UK's Health Secretary, Wes Streeting, has also advised women to ignore Trump's claims and reassure them that paracetamol is safe to use when pregnant and in pain or suffering a fever.