Study Finds Modest Link Between Autism Diagnosis and Higher Levels of Lithium in Drinking Water.
A recent study published in the journal JAMA Pediatrics has found a modest association between higher levels of lithium in drinking water and an increased risk of autism spectrum disorder (ASD) in children. However, experts caution that this link is not conclusive and requires further research to confirm its validity.
According to the study, approximately 1 in 36 children in the US is diagnosed with ASD each year. While the exact cause of autism remains unknown, scientists have been exploring potential environmental causes, including exposure to certain substances like lithium.
Lithium is an alkali metal that can be found naturally in some food and ground water. It's used in batteries, grease, air conditioners, and as a treatment for bipolar disorder and some blood disorders. The levels of lithium in US drinking water are not regulated by the US Geological Survey.
The study, which analyzed data from Denmark, found that pregnant women who consumed water with higher levels of lithium had an increased risk of their child being diagnosed with ASD. Specifically, children born to mothers who consumed the second and third highest exposure levels of lithium during pregnancy were 24% to 26% more likely to be diagnosed with ASD compared to those at lower exposure levels.
However, experts emphasize that this association does not necessarily imply a direct link between lithium exposure and autism diagnosis. Dr. Beate Ritz, co-author of the study, notes that "any drinking water contaminants that may affect the developing human brain deserve intense scrutiny." However, more research is needed to confirm these findings and rule out alternative explanations.
The implications of this finding are complex, with some studies suggesting that higher levels of lithium in water may be linked to health benefits such as lower rates of hospitalization for psychiatric disorders and suicide. Nevertheless, Dr. David C. Bellinger cautions that "until the basic biology of ASD is better understood, it will be difficult to distinguish causal from spurious associations."
Other researchers have raised similar concerns, with Dr. Max Wiznitzer noting that studies on lithium exposure in pregnant women show no correlation with autism risk. He emphasizes that causation is not proven and that a viable biological mechanism linking small amounts of lithium in water supply to ASD diagnosis remains elusive.
The study's findings highlight the need for further research into potential environmental causes of autism, as well as the complexity of interpreting associations between exposure to certain substances and disease risk. As Dr. Wiznitzer notes, "there's a lot of speculation about environmental factors... We have to figure out how to safely navigate them."
A recent study published in the journal JAMA Pediatrics has found a modest association between higher levels of lithium in drinking water and an increased risk of autism spectrum disorder (ASD) in children. However, experts caution that this link is not conclusive and requires further research to confirm its validity.
According to the study, approximately 1 in 36 children in the US is diagnosed with ASD each year. While the exact cause of autism remains unknown, scientists have been exploring potential environmental causes, including exposure to certain substances like lithium.
Lithium is an alkali metal that can be found naturally in some food and ground water. It's used in batteries, grease, air conditioners, and as a treatment for bipolar disorder and some blood disorders. The levels of lithium in US drinking water are not regulated by the US Geological Survey.
The study, which analyzed data from Denmark, found that pregnant women who consumed water with higher levels of lithium had an increased risk of their child being diagnosed with ASD. Specifically, children born to mothers who consumed the second and third highest exposure levels of lithium during pregnancy were 24% to 26% more likely to be diagnosed with ASD compared to those at lower exposure levels.
However, experts emphasize that this association does not necessarily imply a direct link between lithium exposure and autism diagnosis. Dr. Beate Ritz, co-author of the study, notes that "any drinking water contaminants that may affect the developing human brain deserve intense scrutiny." However, more research is needed to confirm these findings and rule out alternative explanations.
The implications of this finding are complex, with some studies suggesting that higher levels of lithium in water may be linked to health benefits such as lower rates of hospitalization for psychiatric disorders and suicide. Nevertheless, Dr. David C. Bellinger cautions that "until the basic biology of ASD is better understood, it will be difficult to distinguish causal from spurious associations."
Other researchers have raised similar concerns, with Dr. Max Wiznitzer noting that studies on lithium exposure in pregnant women show no correlation with autism risk. He emphasizes that causation is not proven and that a viable biological mechanism linking small amounts of lithium in water supply to ASD diagnosis remains elusive.
The study's findings highlight the need for further research into potential environmental causes of autism, as well as the complexity of interpreting associations between exposure to certain substances and disease risk. As Dr. Wiznitzer notes, "there's a lot of speculation about environmental factors... We have to figure out how to safely navigate them."